New study tracks rare genetic heart condition to guide future treatments
NCT ID NCT05981092
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows about 35 people with dilated cardiomyopathy caused by a BAG3 gene mutation, a condition that weakens the heart muscle. Over three years, researchers will monitor heart function, symptoms, and quality of life using tests like imaging and blood work. The goal is to understand how the disease progresses naturally, which could help design better treatments in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help researchers better understand BAG3-related heart disease and design future treatments.
What could go wrong
This is an observational study with only 35 participants, so findings may not apply to everyone. It does not test any new treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research Site
Palo Alto, California, 94305, United States
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Research Site
Aurora, Colorado, 80045, United States
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Research Site
Boston, Massachusetts, 02115, United States
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Research Site
Rochester, Minnesota, 55905, United States
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Research Site
The Bronx, New York, 10467, United States
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Research Site
Philadelphia, Pennsylvania, 19104, United States
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Research Site
Amsterdam, Amsterdam, 1105 AZ, Netherlands
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Research Site
Maastricht, Maastricht, 6229 HX, Netherlands
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Research Site
Warsaw, Warszawa, 04-628, Poland
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Research Site
A Coruña, A Coruna, 15006, Spain
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Research Site
Madrid, Madrid, 28041, Spain
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Research Site
Majadahonda, Madrid, 28222, Spain
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Research Site
El Palmar, Murcia, 30120, Spain
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Research Site
Harefield, London, UB9 6JH, United Kingdom
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Research Site
London, London, EC1A 7BE, United Kingdom