Virus vs. superbug: new therapy tested for cystic fibrosis patients
NCT ID NCT05453578
Summary
This early-phase trial tested the safety and initial effectiveness of a single-dose, intravenous therapy made from special viruses called bacteriophages. The goal was to see if these viruses could safely target and reduce levels of Pseudomonas aeruginosa, a harmful bacteria that commonly infects the lungs of people with cystic fibrosis. The study involved 72 adults with CF who carried this bacteria, comparing different doses of the therapy to a placebo.
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Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77030-3411, United States
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Emory University - Adult Cystic Fibrosis Program
Atlanta, Georgia, 30324, United States
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Johns Hopkins University
Baltimore, Maryland, 21205, United States
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Michigan Medicine
Ann Arbor, Michigan, 48109, United States
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Northwell Health
New Hyde Park, New York, 11050, United States
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Stanford University
Stanford, California, 94305, United States
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The University of Arizona - Banner University Medical Center Tucson Campus - Tucson
Tucson, Arizona, 85724-0001, United States
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University of California Davis Health
Sacramento, California, 95816, United States
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University of California Los Angeles Medical Center - Westwood Clinic
Los Angeles, California, 90095, United States
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University of California, San Diego
La Jolla, California, 92037, United States
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University of California, San Diego (UCSD) - Antiviral Research Center (AVRC)
La Jolla, California, 92121, United States
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University of Minnesota Medical Center
Minneapolis, Minnesota, 55455-0341, United States
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University of South Florida/Tampa General Hospital
Tampa, Florida, 22612, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of Virginia
Charlottesville, Virginia, 22908, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
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Yale North Haven Medical Center- Winchester Center for Lung Disease
North Haven, Connecticut, 06473, United States
Conditions
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