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Back muscles hold clues for treating recurrent low back pain

NCT ID NCT05851196

Symptom relief Sponsor: Hasselt University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Researchers compare back muscle characteristics in people with recurrent non-specific low back pain and healthy controls to identify distinct muscle profiles. Patients then receive a 16-week proprioceptive training program tailored by a physiotherapist, with exercises integrated into daily activities. The study measures changes in muscle structure, activation, and postural control to see if this approach eases pain and disability.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a 16-week proprioceptive exercise training program tailored by a physiotherapist
What this could lead to
If the training helps, it could give physiotherapists a clearer way to match exercise programs to each patient's back muscle profile, potentially reducing pain and disability for people with recurrent low back pain.
What could go wrong
This is a small study of 100 people, and exercise programs do not work for everyone. The results may not apply to all types of low back pain, and any improvements might not last after training ends.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2024

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Flemish Brabant

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients with non-specific low back pain: * Aged 18-60 years * Non-specific low back pain without radicular leg pain * Mechanical low back pain with episodes of \<4 on the numerical pain rating scale and episodes of \>6 on the numerical pain rating scale * Non-specific low back pain for three months or more * Score of 20% or more on the Modified Low Back Pain Disability Questionnaire * Informed consent to participate Healthy controls: * Aged 18-60 years * No history of low back pain needing medical treatment or resulting in a limited activity level * No low back pain in the previous six months * Informed consent to participate Exclusion Criteria: * Pregnancy * Previous trauma or surgery to the spine, pelvis or lower limbs * Structural spinal deformity (e.g., scoliosis) * Neurological, neuromuscular, respiratory or systemic disease * Central sensitization: score of 50/100 or more on the Central Sensitization Inventory * Specific vestibular or balance problems * Acute lower limb or neck problems * Body mass index of 30 kg/m² or more

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Conditions

The condition(s) this trial relates to.

Low Back Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Back pain lower back chronic Low back pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Rehabilitation Sciences, KU Leuven

    RECRUITING

    Leuven, 3001, Belgium

  • REVAL Rehabilitation Research Center, Hasselt University

    RECRUITING

    Diepenbeek, 3500, Belgium

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