Could a Once-Every-Few-Weeks shot replace daily pills for schizophrenia?

NCT ID NCT07722728

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This trial compares a new long-acting injectable form of the schizophrenia drug cariprazine (called B2227) with the standard oral version, Vraylar. Researchers want to see how the body absorbs and processes each version, and whether the injectable is safe and tolerable. The study involves 84 adults with schizophrenia who receive either a single injection of B2227 or multiple doses of oral Vraylar.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a long-acting injectable form of the schizophrenia drug cariprazine, called B2227
What this could lead to
If successful, this could offer people with schizophrenia a longer-acting treatment option that requires less frequent dosing.
What could go wrong
This is an early-to-mid-stage trial with only 84 participants, so results may not apply broadly. Side effects of cariprazine can include movement disorders and sedation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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