New hope for lung cancer patients: experimental drug shows promise in early trial

NCT ID NCT01802632

First seen Apr 30, 2026 · Last updated May 16, 2026 · Updated 4 times

Summary

This study tested a new drug called AZD9291 in 603 people with advanced non-small cell lung cancer whose tumors had started growing again after previous targeted therapy. The main goals were to find the safest and most effective dose, measure how the drug moves through the body, and see if it can shrink tumors. The results helped decide the best dose for future studies.

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Contacts and locations

Locations

  • Research Site

    Aurora, Colorado, 80045, United States

  • Research Site

    Atlanta, Georgia, 30322, United States

  • Research Site

    Boston, Massachusetts, 02114, United States

  • Research Site

    Boston, Massachusetts, 02215, United States

  • Research Site

    Charlotte, North Carolina, 28204, United States

  • Research Site

    Nashville, Tennessee, 37232, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    Heidelberg, 3084, Australia

  • Research Site

    Kogarah, 2217, Australia

  • Research Site

    Nedlands, 6009, Australia

  • Research Site

    Pierre-Bénite, 69310, France

  • Research Site

    Saint-Herblain, 44805, France

  • Research Site

    Villejuif, 94800, France

  • Research Site

    Cologne, 50924, Germany

  • Research Site

    Essen, 45122, Germany

  • Research Site

    Würzburg, 97080, Germany

  • Research Site

    Genova, 16100, Italy

  • Research Site

    Orbassano, 10043, Italy

  • Research Site

    Roma, 00144, Italy

  • Research Site

    Chiba, 260-8717, Japan

  • Research Site

    Fukuoka, 811-1395, Japan

  • Research Site

    Fukuoka, 812-8582, Japan

  • Research Site

    Habikino-shi, 583-8588, Japan

  • Research Site

    Hirakata-shi, 573-1191, Japan

  • Research Site

    Hiroshima, 730-8518, Japan

  • Research Site

    Kanazawa, 920-8641, Japan

  • Research Site

    Kashiwa, 227-8577, Japan

  • Research Site

    Kobe, 650-0047, Japan

  • Research Site

    Matsuyama, 790-0007, Japan

  • Research Site

    Okayama, 700-8558, Japan

  • Research Site

    Shinjuku-ku, 160-0023, Japan

  • Research Site

    Sunto-gun, 411-8777, Japan

  • Research Site

    Takatsuki-shi, 569-8686, Japan

  • Research Site

    Yokohama, 221-0855, Japan

  • Research Site

    Seoul, 03080, South Korea

  • Research Site

    Seoul, 03722, South Korea

  • Research Site

    Seoul, 05505, South Korea

  • Research Site

    Seoul, 6351, South Korea

  • Research Site

    Madrid, 08035, Spain

  • Research Site

    Madrid, 28041, Spain

  • Research Site

    Seville, 41013, Spain

  • Research Site

    Tainan, 704, Taiwan

  • Research Site

    Taipei, 10002, Taiwan

  • Research Site

    Manchester, M20 4BX, United Kingdom

  • Research Site

    Newcastle upon Tyne, NE7 7DN, United Kingdom

Conditions

Explore the condition pages connected to this study.