New antibody drug takes on tough cancers
NCT ID NCT04931654
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests an experimental drug called AZD7789 in people with advanced lung, stomach, or gastroesophageal cancer that cannot be removed by surgery. The drug is a bispecific antibody designed to help the immune system attack cancer cells. The trial aims to check if the drug is safe and whether it can shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AZD7789 (a bispecific antibody that targets PD-1 and TIM-3 proteins on immune cells)
- What this could lead to
- If it works, this could offer a new treatment option for people with advanced solid tumors that have not responded to other therapies.
- What could go wrong
- This is an early-phase trial with a small number of participants, so the drug may not prove effective or may cause unexpected side effects. Success is far from guaranteed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Research Site
Atlanta, Georgia, 30322, United States
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Research Site
Fort Wayne, Indiana, 46804, United States
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Research Site
New York, New York, 10029, United States
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Research Site
Nashville, Tennessee, 37203, United States
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Research Site
Toronto, Ontario, M5G 2M9, Canada
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Research Site
Beijing, 100142, China
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Research Site
Guangzhou, 510060, China
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Research Site
Bordeaux, 33076, France
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Research Site
Rennes, 35000, France
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Research Site
Villejuif, 94805, France
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Research Site
Tbilisi, 0112, Georgia
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Research Site
Chūōku, 104-0045, Japan
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Research Site
Kashiwa, 277-8577, Japan
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Research Site
Chisinau, MD-2025, Moldova
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Research Site
Amsterdam, 1066 CX, Netherlands
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Research Site
Barcelona, 08035, Spain
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Research Site
Madrid, 28027, Spain
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Research Site
Ankara, 06010, Turkey (Türkiye)
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Research Site
Ankara, 06200, Turkey (Türkiye)
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Research Site
Ankara, 06800, Turkey (Türkiye)
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Research Site
Cordaleo, 35575, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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- Can immunotherapy be safely used in early lung cancer? a Real-World study investigates