New drug AZD4956 targets Hard-to-Treat tumors in early human trial

NCT ID NCT07446855

First seen Mar 04, 2026 · Last updated May 16, 2026 · Updated 7 times

Summary

This study tests a new experimental drug called AZD4956, alone or with other cancer drugs, in people with advanced or metastatic solid tumors that have a specific DNA repair defect (HRR deficiency). The main goals are to check safety, find the right dose, and see if the drug can shrink tumors or slow their growth. About 180 adults with these hard-to-treat cancers will take part in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    NOT_YET_RECRUITING

    New York, New York, 10065, United States

  • Research Site

    NOT_YET_RECRUITING

    Providence, Rhode Island, 02903, United States

  • Research Site

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

  • Research Site

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Research Site

    NOT_YET_RECRUITING

    Melbourne, 3000, Australia

  • Research Site

    NOT_YET_RECRUITING

    Westmead, 2145, Australia

  • Research Site

    NOT_YET_RECRUITING

    Chūōku, 104-0045, Japan

  • Research Site

    NOT_YET_RECRUITING

    Kashiwa, 277-8577, Japan

  • Research Site

    NOT_YET_RECRUITING

    Seoul, 03080, South Korea

  • Research Site

    NOT_YET_RECRUITING

    Seoul, 120-752, South Korea

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 08023, Spain

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 08036, Spain

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 8035, Spain

  • Research Site

    NOT_YET_RECRUITING

    Logroño, 26006, Spain

  • Research Site

    NOT_YET_RECRUITING

    Pozuelo de Alarcón, 28223, Spain

  • Research Site

    NOT_YET_RECRUITING

    Seville, 41013, Spain

  • Research Site

    NOT_YET_RECRUITING

    London, SE1 9RT, United Kingdom

  • Research Site

    NOT_YET_RECRUITING

    Sutton, SM25PT, United Kingdom

Conditions

Explore the condition pages connected to this study.