AstraZeneca launches human tests for bird flu vaccines

NCT ID NCT07128615

Ongoing ⭐️ VACCINE ⭐️ Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 21, 2026 · Updated 3 times

Summary

This study tests two experimental vaccines, AZD4117 and AZD5315, designed to protect against certain strains of avian influenza (bird flu), specifically H5N1 and H7N9. Around 405 healthy adults will receive either a vaccine or a placebo to see if the vaccines are safe and trigger a strong immune response. The trial is currently active but not recruiting new participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AZD4117 and AZD5315 vaccines
What this could lead to: If successful, these vaccines could help protect people against certain bird flu strains, potentially preventing a future pandemic.
What could go wrong: This is an early-phase trial focused on safety and immune response, not yet proven to prevent infection. The vaccines may not work as hoped or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

avian influenza prevention target swine influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLUENZA A

Contacts and locations

Locations

Research Site

Long Beach, California, 90815, United States
Research Site

Rolling Hills Estates, California, 90274, United States
Research Site

Hialeah, Florida, 33012, United States
Research Site

Stockbridge, Georgia, 30281, United States
Research Site

Chicago, Illinois, 60640, United States
Research Site

Lenexa, Kansas, 66219, United States
Research Site

Kansas City, Missouri, 64114, United States
Research Site

Omaha, Nebraska, 68134, United States
Research Site

Las Vegas, Nevada, 89119, United States
Research Site

Cincinnati, Ohio, 45212, United States
Research Site

Edmond, Oklahoma, 73013, United States
Research Site

North Charleston, South Carolina, 29405, United States
Research Site

Austin, Texas, 78745, United States
Research Site

West Jordan, Utah, 84088, United States

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