New IRAK4 blocker AZD2962 enters human trials for Hard-to-Treat blood cancers

NCT ID NCT07064122

First seen Nov 17, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This study tests a new drug called AZD2962, which blocks a protein (IRAK4) involved in cancer growth. It is for people with certain blood cancers (MDS or CMML) that have not responded to standard treatments. The main goals are to check safety, find the right dose, and see if the drug helps shrink or control the cancer. About 72 participants will take the drug alone or with other medicines.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

  • Research Site

    RECRUITING

    Tampa, Florida, 33612, United States

  • Research Site

    RECRUITING

    Houston, Texas, 77030, United States

  • Research Site

    RECRUITING

    Heidelberg, 3084, Australia

  • Research Site

    RECRUITING

    Melbourne, 3000, Australia

  • Research Site

    RECRUITING

    Shinagawa-ku, 141-0022, Japan

  • Research Site

    RECRUITING

    Yoshida-gun, 910-1193, Japan

  • Research Site

    WITHDRAWN

    Seoul, 05505, South Korea

  • Research Site

    WITHDRAWN

    Seoul, 3722, South Korea

  • Research Site

    RECRUITING

    Barcelona, 08035, Spain

  • Research Site

    RECRUITING

    Madrid, 28027, Spain

  • Research Site

    RECRUITING

    Madrid, 28033, Spain

  • Research Site

    RECRUITING

    Pamplona, 31008, Spain

  • Research Site

    RECRUITING

    Salamanca, 37007, Spain

  • Research Site

    WITHDRAWN

    Valencia, 46026, Spain

  • Research Site

    NOT_YET_RECRUITING

    Kaohsiung City, 83301, Taiwan

  • Research Site

    NOT_YET_RECRUITING

    Tainan, 70403, Taiwan

  • Research Site

    RECRUITING

    Taipei, 100, Taiwan

  • Research Site

    RECRUITING

    London, SE5 9RS, United Kingdom

  • Research Site

    RECRUITING

    London, W1T 7HA, United Kingdom

  • Research Site

    RECRUITING

    Manchester, M20 4BX, United Kingdom

Conditions

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