New drug trial targets genetic cause of kidney failure

NCT ID NCT06824987

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called AZD2373 to see if it can slow kidney damage in people with a specific genetic form of kidney disease (APOL1-mediated). About 96 adults with the high-risk APOL1 genes will receive either the drug or a placebo for at least 30 weeks. The main goal is to see if the drug reduces protein in the urine, a key sign of kidney damage.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Alabaster, Alabama, 35007, United States
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Birmingham, Alabama, 35205, United States
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Irondale, Alabama, 35210, United States
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Beverly Hills, California, 90211, United States
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Gardena, California, 90247, United States
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Los Angeles, California, 90095, United States
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Valencia, California, 91355, United States
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Brandon, Florida, 33511, United States
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Miami, Florida, 33126, United States
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Miami, Florida, 33173, United States
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Orlando, Florida, 32808, United States
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Pompano Beach, Florida, 33060, United States
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Atlanta, Georgia, 30322, United States
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Augusta, Georgia, 30909, United States
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Augusta, Georgia, 30912, United States
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Columbus, Georgia, 31901, United States
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Columbus, Georgia, 31904, United States
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Duluth, Georgia, 30096, United States
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Hinesville, Georgia, 31313, United States
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Lawrenceville, Georgia, 30046, United States
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Macon, Georgia, 31210, United States
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Macon, Georgia, 31217, United States
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Marietta, Georgia, 30067, United States
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Savannah, Georgia, 31406, United States
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Stockbridge, Georgia, 30281, United States
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Chicago, Illinois, 60612, United States
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Hinsdale, Illinois, 60521, United States
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Lafayette, Louisiana, 70508, United States
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New Orleans, Louisiana, 70112, United States
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Bethesda, Maryland, 20889, United States
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Potomac, Maryland, 20854, United States
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Boston, Massachusetts, 02114, United States
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Roseville, Michigan, 48066, United States
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Minneapolis, Minnesota, 55455, United States
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Tupelo, Mississippi, 38801, United States
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Brooklyn, New York, 11203, United States
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Brooklyn, New York, 11221, United States
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Laurelton, New York, 11413, United States
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New York, New York, 10010, United States
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Cary, North Carolina, 27511, United States
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Durham, North Carolina, 27705, United States
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Fayetteville, North Carolina, 28304, United States
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Gastonia, North Carolina, 28054, United States
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Greenville, North Carolina, 27834, United States
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Jacksonville, North Carolina, 28546, United States
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Kinston, North Carolina, 28501, United States
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Winston-Salem, North Carolina, 27103, United States
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Winston-Salem, North Carolina, 27157, United States
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Cincinnati, Ohio, 45246, United States
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Columbus, Ohio, 43210, United States
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Philadelphia, Pennsylvania, 19104, United States
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Anderson, South Carolina, 29621, United States
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Columbia, South Carolina, 29203, United States
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Orangeburg, South Carolina, 29118, United States
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Spartanburg, South Carolina, 29306, United States
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Chattanooga, Tennessee, 37404, United States
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Nashville, Tennessee, 37232, United States
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Conroe, Texas, 77384, United States
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Dallas, Texas, 75234, United States
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Dallas, Texas, 75235, United States
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Houston, Texas, 77054, United States
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Mesquite, Texas, 75149, United States
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Pearland, Texas, 77584, United States
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San Antonio, Texas, 78212, United States
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WITHDRAWN

Alexandria, Virginia, 22311, United States
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Norfolk, Virginia, 23510, United States
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Richmond, Virginia, 23298, United States
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Birmingham, B15 2WB, United Kingdom
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Leicester, Le5 4PW, United Kingdom
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Liverpool, L22 0LG, United Kingdom
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London, NW3 2QG, United Kingdom
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London, SE1 9RT, United Kingdom
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London, SE5 8AZ, United Kingdom
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London, SM5 1AA, United Kingdom
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London, SW17 0QT, United Kingdom
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London, SW7 2AZ, United Kingdom
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Manchester, M13 9WL, United Kingdom

Conditions

Explore the condition pages connected to this study.

APOL1-MEDIATED KIDNEY DISEASE