New hope for lymphoma patients: drug duo may replace harsh chemo

NCT ID NCT06549595

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 30 times

Summary

This study tests whether a new drug (AZD0486) plus rituximab works better than standard chemotherapy plus rituximab for people with untreated follicular lymphoma. About 1,018 adults will take part. The goal is to see if the new combination can control the disease longer and with fewer side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Research Site
NOT_YET_RECRUITING

Darlinghurst, 2010, Australia
Research Site
RECRUITING

Garran, 2605, Australia
Research Site
RECRUITING

Heidelberg, 3084, Australia
Research Site
RECRUITING

Macquarie University, 2109, Australia
Research Site
RECRUITING

Nedlands, 6009, Australia
Research Site
NOT_YET_RECRUITING

Brussels, 1070, Belgium
Research Site
NOT_YET_RECRUITING

Brussels, 1090, Belgium
Research Site
NOT_YET_RECRUITING

Ghent, 9000, Belgium
Research Site
NOT_YET_RECRUITING

Mechelen, 2800, Belgium
Research Site
RECRUITING

Porto Alegre, 90035-003, Brazil
Research Site
RECRUITING

São Paulo, 04501-000, Brazil
Research Site
RECRUITING

São Paulo, 05652-900, Brazil
Research Site
NOT_YET_RECRUITING

Winnipeg, Manitoba, R3E 0V9, Canada
Research Site
RECRUITING

Halifax, Nova Scotia, B3H 2Y9, Canada
Research Site
WITHDRAWN

Barrie, Ontario, L4M 6M2, Canada
Research Site
RECRUITING

Hamilton, Ontario, L8V 5C2, Canada
Research Site
RECRUITING

Oshawa, Ontario, L1G 2B9, Canada
Research Site
RECRUITING

Toronto, Ontario, M5G 1X6, Canada
Research Site
RECRUITING

Chicoutimi, Quebec, G7H 5H6, Canada
Research Site
RECRUITING

Montreal, Quebec, H4J 1C5, Canada
Research Site
RECRUITING

Québec, Quebec, G1J 1Z4, Canada
Research Site
RECRUITING

Saint-Jérôme, Quebec, J7Z 2V4, Canada
Research Site
RECRUITING

Beijing, 100044, China
Research Site
RECRUITING

Beijing, 100142, China
Research Site
NOT_YET_RECRUITING

Beijing, 100730, China
Research Site
NOT_YET_RECRUITING

Changchun, 130021, China
Research Site
NOT_YET_RECRUITING

Changsha, 410013, China
Research Site
RECRUITING

Chengdu, 610078, China
Research Site
RECRUITING

Chongqing, 400030, China
Research Site
NOT_YET_RECRUITING

Fuzhou, 350001, China
Research Site
RECRUITING

Guangzhou, 510000, China
Research Site
RECRUITING

Guangzhou, 510060, China
Research Site
NOT_YET_RECRUITING

Guangzhou, 510100, China
Research Site
RECRUITING

Hangzhou, 310003, China
Research Site
NOT_YET_RECRUITING

Hangzhou, 310022, China
Research Site
RECRUITING

Harbin, 150081, China
Research Site
RECRUITING

Hefei, 230031, China
Research Site
RECRUITING

Lanzhou, 730000, China
Research Site
RECRUITING

Nanchang, 330006, China
Research Site
RECRUITING

Nanchang, 330029, China
Research Site
NOT_YET_RECRUITING

Nanjing, 210029, China
Research Site
RECRUITING

Nanning, 530021, China
Research Site
RECRUITING

Shandong, 250117, China
Research Site
RECRUITING

Shanghai, 200065, China
Research Site
RECRUITING

Shanghai, 20032, China
Research Site
NOT_YET_RECRUITING

Shenyang, 110001, China
Research Site
RECRUITING

Shenyang, 110004, China
Research Site
NOT_YET_RECRUITING

Shijiazhuang, 054001, China
Research Site
RECRUITING

Suzhou, 215006, China
Research Site
RECRUITING

Tianjin, 300020, China
Research Site
NOT_YET_RECRUITING

Wenzhou, 325000, China
Research Site
RECRUITING

Wuhan, 430079, China
Research Site
RECRUITING

Xi'an, 710061, China
Research Site
RECRUITING

Xiamen, 361003, China
Research Site
NOT_YET_RECRUITING

Zhengzhou, 450000, China
Research Site
RECRUITING

Zhengzhou, 450008, China
Research Site
NOT_YET_RECRUITING

Brno, 625 00, Czechia
Research Site
NOT_YET_RECRUITING

Hradec Králové, 500 05, Czechia
Research Site
NOT_YET_RECRUITING

Prague, 12808, Czechia
Research Site
NOT_YET_RECRUITING

Aalborg, 9100, Denmark
Research Site
NOT_YET_RECRUITING

Copenhagen, 2100, Denmark
Research Site
NOT_YET_RECRUITING

Odense C, 5000, Denmark
Research Site
NOT_YET_RECRUITING

Roskilde, 4000, Denmark
Research Site
WITHDRAWN

Helsinki, 00029, Finland
Research Site
WITHDRAWN

Kuopio, 70029, Finland
Research Site
WITHDRAWN

Tampere, 33520, Finland
Research Site
RECRUITING

Hong Kong, 999077, Hong Kong
Research Site
RECRUITING

Shatin, 00000, Hong Kong
Research Site
NOT_YET_RECRUITING

Budapest, 1088, Hungary
Research Site
WITHDRAWN

Budapest, 1122, Hungary
Research Site
NOT_YET_RECRUITING

Debrecen, 4032, Hungary
Research Site
NOT_YET_RECRUITING

Győr, 9024, Hungary
Research Site
NOT_YET_RECRUITING

Kaposvár, 7400, Hungary
Research Site
NOT_YET_RECRUITING

Nyíregyháza, 4400, Hungary
Research Site
NOT_YET_RECRUITING

Pécs, 7624, Hungary
Research Site
NOT_YET_RECRUITING

Szeged, 6725, Hungary
Research Site
NOT_YET_RECRUITING

Delhi, 110029, India
Research Site
NOT_YET_RECRUITING

Delhi, 110085, India
Research Site
NOT_YET_RECRUITING

Fort Wayne, Indiana, 46804, United States
Research Site
NOT_YET_RECRUITING

Des Moines, Iowa, 50309, United States
Research Site
NOT_YET_RECRUITING

Iowa City, Iowa, 52242, United States
Research Site
NOT_YET_RECRUITING

Lexington, Kentucky, 40536, United States
Research Site
NOT_YET_RECRUITING

Louisville, Kentucky, 40207, United States
Research Site
NOT_YET_RECRUITING

Baton Rouge, Louisiana, 70808, United States
Research Site
NOT_YET_RECRUITING

Baltimore, Maryland, 21201, United States
Research Site
NOT_YET_RECRUITING

Bethesda, Maryland, 20817, United States
Research Site
NOT_YET_RECRUITING

Columbia, Maryland, 21044, United States
Research Site
NOT_YET_RECRUITING

Boston, Massachusetts, 02114, United States
Research Site
NOT_YET_RECRUITING

Boston, Massachusetts, 02215, United States
Research Site
NOT_YET_RECRUITING

Ann Arbor, Michigan, 48109, United States
Research Site
NOT_YET_RECRUITING

Detroit, Michigan, 48201, United States
Research Site
NOT_YET_RECRUITING

Ypsilanti, Michigan, 48197, United States
Research Site
NOT_YET_RECRUITING

Saint Paul, Minnesota, 55102, United States
Research Site
NOT_YET_RECRUITING

Springfield, Missouri, 65807, United States
Research Site
NOT_YET_RECRUITING

Hackensack, New Jersey, 07601, United States
Research Site
NOT_YET_RECRUITING

New Brunswick, New Jersey, 08901, United States
Research Site
NOT_YET_RECRUITING

New Hyde Park, New York, 11042, United States
Research Site
NOT_YET_RECRUITING

New York, New York, 10016, United States
Research Site
NOT_YET_RECRUITING

New York, New York, 10032, United States
Research Site
NOT_YET_RECRUITING

New York, New York, 10065, United States
Research Site
NOT_YET_RECRUITING

Charlotte, North Carolina, 28204, United States
Research Site
NOT_YET_RECRUITING

Winston-Salem, North Carolina, 27103, United States
Research Site
NOT_YET_RECRUITING

Blue Ash, Ohio, 45242, United States
Research Site
NOT_YET_RECRUITING

Columbus, Ohio, 43210, United States
Research Site
NOT_YET_RECRUITING

Eugene, Oregon, 97401, United States
Research Site
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
Research Site
NOT_YET_RECRUITING

Nashville, Tennessee, 37203, United States
Research Site
NOT_YET_RECRUITING

Shenandoah, Texas, 77380, United States
Research Site
NOT_YET_RECRUITING

Tyler, Texas, 75702, United States
Research Site
NOT_YET_RECRUITING

Salt Lake City, Utah, 84112, United States
Research Site
NOT_YET_RECRUITING

Fairfax, Virginia, 22031, United States
Research Site
NOT_YET_RECRUITING

Richmond, Virginia, 23219, United States
Research Site
NOT_YET_RECRUITING

Tacoma, Washington, 98405, United States
Research Site
NOT_YET_RECRUITING

Madison, Wisconsin, 53792, United States
Research Site
NOT_YET_RECRUITING

Gurugram, 122002, India
Research Site
NOT_YET_RECRUITING

Kolkata, 700160, India
Research Site
NOT_YET_RECRUITING

Nashik, 422002, India
Research Site
NOT_YET_RECRUITING

Surat, 396007, India
Research Site
NOT_YET_RECRUITING

Thiruvananthapuram, 695011, India
Research Site
RECRUITING

Bunkyō City, 113-8677, Japan
Research Site
RECRUITING

Chiba, 260-8717, Japan
Research Site
RECRUITING

Chuo-shi, 409-3898, Japan
Research Site
RECRUITING

Fukuoka, 812-8582, Japan
Research Site
RECRUITING

Hirakata-shi, 573-1191, Japan
Research Site
RECRUITING

Kobe, 650-0047, Japan
Research Site
RECRUITING

Kōtoku, 135-8550, Japan
Research Site
RECRUITING

Kumamoto, 860-8556, Japan
Research Site
RECRUITING

Kurashiki-shi, 710-8602, Japan
Research Site
RECRUITING

Kyoto, 602-8566, Japan
Research Site
RECRUITING

Minatoku, 105-8470, Japan
Research Site
RECRUITING

Okayama, 700-8558, Japan
Research Site
RECRUITING

Osaka, 541-8567, Japan
Research Site
RECRUITING

Sapporo, 003-0006, Japan
Research Site
RECRUITING

Sapporo, 060-8638, Japan
Research Site
RECRUITING

Sunto-gun, 411-8777, Japan
Research Site
RECRUITING

Toyoake-shi, 470-1192, Japan
Research Site
RECRUITING

Yamagata, 990-9585, Japan
Research Site
RECRUITING

Yokohama, 241-8515, Japan
Research Site
WITHDRAWN

Gliwice, 44-102, Poland
Research Site
NOT_YET_RECRUITING

San Juan, 00918, Puerto Rico
Research Site
RECRUITING

Busan, 49201, South Korea
Research Site
RECRUITING

Busan, 49241, South Korea
Research Site
RECRUITING

Goyang-si, 10408, South Korea
Research Site
RECRUITING

Jeonnam, 519-763, South Korea
Research Site
RECRUITING

Seoul, 03080, South Korea
Research Site
RECRUITING

Seoul, 03722, South Korea
Research Site
RECRUITING

Seoul, 05505, South Korea
Research Site
RECRUITING

Seoul, 06351, South Korea
Research Site
RECRUITING

Seoul, 06591, South Korea
Research Site
NOT_YET_RECRUITING

Barcelona, 08035, Spain
Research Site
NOT_YET_RECRUITING

Barcelona, 8036, Spain
Research Site
NOT_YET_RECRUITING

El Palmar, 30120, Spain
Research Site
NOT_YET_RECRUITING

Girona, 17007, Spain
Research Site
NOT_YET_RECRUITING

Las Palmas de Gran Canaria, 35020, Spain
Research Site
NOT_YET_RECRUITING

Madrid, 28040, Spain
Research Site
NOT_YET_RECRUITING

Madrid, 28041, Spain
Research Site
NOT_YET_RECRUITING

Oviedo, 33011, Spain
Research Site
NOT_YET_RECRUITING

Pamplona, 31008, Spain
Research Site
NOT_YET_RECRUITING

Santander, 39008, Spain
Research Site
WITHDRAWN

Falun, 79182, Sweden
Research Site
WITHDRAWN

Uppsala, 75185, Sweden
Research Site
RECRUITING

Changhua, 50006, Taiwan
Research Site
RECRUITING

Kaohsiung City, 80756, Taiwan
Research Site
RECRUITING

Kaohsiung City, 833, Taiwan
Research Site
RECRUITING

Lukang Township, 505029, Taiwan
Research Site
RECRUITING

Tainan, 704, Taiwan
Research Site
RECRUITING

Taipei, 106, Taiwan
Research Site
RECRUITING

Bangkok, 10330, Thailand
Research Site
RECRUITING

Bangkok, 10700, Thailand
Research Site
RECRUITING

Chiang Mai, 50200, Thailand
Research Site
RECRUITING

Khon Kaen, 40002, Thailand
Research Site
RECRUITING

London, EC1M6BQ, United Kingdom
Research Site
RECRUITING

London, SE5 9RS, United Kingdom
Research Site
RECRUITING

Newcastle upon Tyne, NE7 7DN, United Kingdom
Research Site
RECRUITING

Norwich, NR4 7UY, United Kingdom
Research Site
RECRUITING

Nottingham, NG5 1PB, United Kingdom
Research Site
RECRUITING

Plymouth, PL6 8DH, United Kingdom
Research Site
NOT_YET_RECRUITING

Southampton, SO16 6YD, United Kingdom
Research Site
NOT_YET_RECRUITING

Huntsville, Alabama, 35805, United States
Research Site
NOT_YET_RECRUITING

Anchorage, Alaska, 99508, United States
Research Site
NOT_YET_RECRUITING

Phoenix, Arizona, 85054, United States
Research Site
NOT_YET_RECRUITING

Clovis, California, 93611, United States
Research Site
NOT_YET_RECRUITING

Los Alamitos, California, 90720, United States
Research Site
NOT_YET_RECRUITING

San Diego, California, 92121, United States
Research Site
NOT_YET_RECRUITING

Santa Monica, California, 90404, United States
Research Site
WITHDRAWN

Aurora, Colorado, 80045, United States
Research Site
NOT_YET_RECRUITING

New Haven, Connecticut, 06510, United States
Research Site
NOT_YET_RECRUITING

Newark, Delaware, 19713, United States
Research Site
NOT_YET_RECRUITING

Jacksonville, Florida, 32224, United States
Research Site
NOT_YET_RECRUITING

Atlanta, Georgia, 30322, United States
Research Site
NOT_YET_RECRUITING

Macon, Georgia, 31201, United States
Research Site
NOT_YET_RECRUITING

Evanston, Illinois, 60201, United States
Research Site
NOT_YET_RECRUITING

Peoria, Illinois, 61615, United States

Conditions

Explore the condition pages connected to this study.

UNTREATED FOLLICULAR LYMPHOMA