New hope for migraine sufferers: drug combo tested after CGRP failure

NCT ID NCT05550207

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 28 times

Summary

This study tested a new migraine medication called AXS-07 (a combination of meloxicam and rizatriptan) in 100 adults whose migraines did not respond well to oral CGRP inhibitors. The goal was to see if the drug could relieve headache pain and the most bothersome symptom without needing rescue medication. The trial is now complete.

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Contacts and locations

Locations

  • Clinical Research Site

    Colton, California, 92324, United States

  • Clinical Research Site

    Fullerton, California, 92835, United States

  • Clinical Research Site

    La Jolla, California, 92037, United States

  • Clinical Research Site

    Los Angeles, California, 90067, United States

  • Clinical Research Site

    Sherman Oaks, California, 91403, United States

  • Clinical Research Site

    Stamford, Connecticut, 06905, United States

  • Clinical Research Site

    DeLand, Florida, 32720, United States

  • Clinical Research Site

    Hallandale, Florida, 33009, United States

  • Clinical Research Site

    Hollywood, Florida, 33024, United States

  • Clinical Research Site

    Miami, Florida, 33126, United States

  • Clinical Research Site

    Ormond Beach, Florida, 31274, United States

  • Clinical Research Site

    Oviedo, Florida, 32765, United States

  • Clinical Research Site

    Pensacola, Florida, 32504, United States

  • Clinical Research Site

    Winter Park, Florida, 32789, United States

  • Clinical Research Site

    Stockbridge, Georgia, 30281, United States

  • Clinical Research Site

    Avon, Indiana, 46123, United States

  • Clinical Research Site

    Boston, Massachusetts, 02131, United States

  • Clinical Research Site

    North Dartmouth, Massachusetts, 02747, United States

  • Clinical Research Site

    Las Vegas, Nevada, 89102, United States

  • Clinical Research Site

    Albuquerque, New Mexico, 87102, United States

  • Clinical Research Site

    The Bronx, New York, 10466, United States

  • Clinical Research Site

    Williamsville, New York, 14221, United States

  • Clinical Research Site

    Philadelphia, Pennsylvania, 19114, United States

  • Clinical Research Site

    Charleston, South Carolina, 29406, United States

  • Clinical Research Site

    Knoxville, Tennessee, 37909, United States

  • Clinical Research Site

    Nashville, Tennessee, 37203, United States

  • Clinical Research Site

    Cypress, Texas, 77429, United States

  • Clinical Research Site

    Sugar Land, Texas, 77478, United States

  • Clinical Research Site

    Salt Lake City, Utah, 84107, United States

  • Clinical Research Site

    Charlottesville, Virginia, 22911, United States

  • Clinical Research Site

    McLean, Virginia, 22101, United States

Conditions

Explore the condition pages connected to this study.