Second dose of CAR t therapy tested for tough lymphoma cases
NCT ID NCT05794958
First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 35 times
Summary
This early-phase study is testing whether a second infusion of the CAR T-cell therapy axicabtagene ciloleucel (Axi-Cel-2) is safe for adults with high-risk large B-cell lymphoma whose cancer came back or didn't respond to the first standard CAR T treatment. About 20 participants will be closely monitored for side effects for 28 days after the second infusion. The goal is to find a way to better control this aggressive cancer, though lifelong monitoring may still be needed.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Stanford University
RECRUITINGPalo Alto, California, 94305, United States
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