New antibody trial targets debilitating skin hardening in transplant patients

NCT ID NCT07011810

Summary

This study is testing a drug called axatilimab for people who develop thick, hard skin after a donor stem cell transplant, a condition called sclerotic chronic graft-versus-host disease (cGVHD). The drug is an antibody given by IV that aims to block cells involved in the scarring and inflammation process. Researchers want to see if it can improve skin hardening or stop it from getting worse in up to 50 adult participants.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Moffitt Cancer Center

    NOT_YET_RECRUITING

    Tampa, Florida, 33612, United States

    Contact

Conditions

Explore the condition pages connected to this study.