New combo therapy shows promise for Tough-to-Treat GIST

NCT ID NCT04258956

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 22 times

Summary

This study tested a combination of two drugs, avelumab and axitinib, in 58 adults with advanced gastrointestinal stromal tumors (GIST) that had stopped responding to standard treatments. The goal was to see if the combination could keep the cancer from growing for at least 3 months. The approach uses immunotherapy plus a targeted drug to try to control the disease.

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Contacts and locations

Locations

  • Maria Sklodowska-Curie National Research Institue of Oncology

    Warsaw, 02-781, Poland

Conditions

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