New drug AWT020 takes on advanced solid tumors

NCT ID NCT06839105

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This phase 1 trial tests a new drug called AWT020, given alone or with other cancer treatments, in people with advanced solid tumors such as non-small cell lung cancer, colorectal cancer, kidney cancer, and melanoma. The main goals are to check the drug's safety, find the best dose, and see if it helps shrink tumors. Participants must have tried standard treatments without success or have no standard options available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AWT020

What this could lead to

If safe and effective, AWT020 could become a new treatment option for people with advanced cancers that have not responded to standard therapies.

What could go wrong

This is an early phase 1 trial with a small number of participants, so the drug may not prove effective or may cause unexpected side effects. Success in this phase does not guarantee later approval.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL ADENOCARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal neoplasm hepatocellular carcinoma melanoma non-small cell lung carcinoma nonpapillary renal cell carcinoma rectum adenocarcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Fujian Cancer Hospital

    RECRUITING

    Fuzhou, Fujian, 350014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Harbin Medical University Cancer Hospital

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150081, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hubei Cancer Hospital

    RECRUITING

    Wuhan, Hubei, 430079, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hunan Cancer Hospital

    RECRUITING

    Changsha, Hunan, 410000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Liaoning Cancer Hospital & Institute

    NOT_YET_RECRUITING

    Shenyang, Liaoning, 110042, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Shanghai Chest Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sun Yat-sen University Cancer Center

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Affiliated Hospital of Henan University of Science & Technology

    NOT_YET_RECRUITING

    Luoyang, Henan, 471099, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Hospital of China Medical University

    RECRUITING

    Shenyang, Liaoning, 400042, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Hospital of Jilin University

    NOT_YET_RECRUITING

    Changchun, Jilin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Yunnan Cancer Hospital

    NOT_YET_RECRUITING

    Kunming, Yunnan, 650118, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Zhejiang Cancer Hospital

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, 310022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact