Could lying on your stomach ease a deadly sickle cell complication?

NCT ID NCT06698120

Not yet recruiting Symptom relief Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether awake prone positioning (lying on the stomach while awake) can help sickle cell patients with severe acute chest syndrome in the ICU. The approach aims to improve oxygen levels and breathing by evening out air flow in the lungs. Fifteen adults will be enrolled to see if the procedure is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: awake prone positioning (a procedure where patients lie on their stomach while awake to help breathing)
What this could lead to: If it works, this could offer a simple, drug-free way to improve oxygen levels and reduce breathing effort during acute chest syndrome.
What could go wrong: This is a very small early study with only 15 participants, so results may not apply widely. The procedure may be uncomfortable or poorly tolerated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE CHEST SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute chest syndrome sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE CHEST SYNDROME SICKLE CELL ANEMIA

Contacts and locations

Locations

Service de Médecine Intensive Réanimation TENON

Paris, 75020, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.