Could lying on your stomach ease a deadly sickle cell complication?

NCT ID NCT06698120

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether awake prone positioning (lying on the stomach while awake) can help sickle cell patients with severe acute chest syndrome in the ICU. The approach aims to improve oxygen levels and breathing by evening out air flow in the lungs. Fifteen adults will be enrolled to see if the procedure is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

awake prone positioning (a procedure where patients lie on their stomach while awake to help breathing)

What this could lead to

If it works, this could offer a simple, drug-free way to improve oxygen levels and reduce breathing effort during acute chest syndrome.

What could go wrong

This is a very small early study with only 15 participants, so results may not apply widely. The procedure may be uncomfortable or poorly tolerated.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute chest syndrome sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Service de Médecine Intensive Réanimation TENON

    Paris, 75020, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••