Experimental pill aims to ease tough schizophrenia symptoms

NCT ID NCT02477670

First seen May 13, 2026 ยท Last updated May 13, 2026

Summary

This study tested an experimental drug called AVP-786 in 145 adults with schizophrenia who still had troubling symptoms despite taking their usual antipsychotic medication. The goal was to see if adding AVP-786 could reduce negative symptoms like lack of motivation and social withdrawal. Participants took either the drug or a placebo for 12 weeks, and researchers measured changes in symptom scores and checked for side effects.

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Contacts and locations

Locations

  • Study site

    Cerritos, California, United States

  • Study site

    Garden Grove, California, United States

  • Study site

    National City, California, United States

  • Study site

    Oakland, California, United States

  • Study site

    San Diego, California, United States

  • Study site

    Washington D.C., District of Columbia, United States

  • Study site

    Orlando, Florida, United States

  • Study site

    Atlanta, Georgia, United States

  • Study site

    Augusta, Georgia, United States

  • Study site

    Chicago, Illinois, United States

  • Study site

    Boston, Massachusetts, United States

  • Study site

    Worcester, Massachusetts, United States

  • Study site

    Grand Rapids, Michigan, United States

  • Study site

    Marlton, New Jersey, United States

  • Study site

    Jamaica, New York, United States

  • Study site

    New York, New York, United States

  • Study site

    Rochester, New York, United States

Conditions

Explore the condition pages connected to this study.