Could a super steroid tame blood cancers? new trial underway

NCT ID NCT04329728

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a drug called AVM0703, a very strong steroid, given as a one-time IV infusion. It aims to see if it is safe and can shrink tumors in people with certain blood cancers like lymphoma and leukemia. The trial will enroll 144 participants aged 12 and older.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AVM0703 (a high-dose steroid given by IV infusion)

What this could lead to

If it works, this could offer a new treatment option for certain blood cancers that are hard to treat.

What could go wrong

This is an early-phase trial with only 144 participants, so results may not apply broadly. The drug is a high-dose steroid, which can cause serious side effects like infections or metabolic issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute biphenotypic leukemia B-cell chronic lymphocytic leukemia B-cell neoplasm diffuse large B-cell lymphoma follicular lymphoma leukemia Leukemia, B-Cell lymphoma lymphoproliferative syndrome mantle cell lymphoma T-cell leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ASCLEPES Research Centers

    RECRUITING

    Weeki Wachee, Florida, 34613, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Baptist Clinical Research Institute

    RECRUITING

    Memphis, Tennessee, 38120, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Gabrail Cancer Center Research,

    RECRUITING

    Canton, Ohio, 44718, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Innovative Clinical Research Institute

    RECRUITING

    Whittier, California, 92705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Los Angeles Cancer Network

    RECRUITING

    Los Angeles, California, 90017, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Norton Cancer Institute

    RECRUITING

    Louisville, Kentucky, 40207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Oncology Hematology West P.C. dba Nebraska Cancer Specialists

    RECRUITING

    Omaha, Nebraska, 68124, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UCLA Medical Center of Hematology/Oncology

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Illinois at Chicago Cancer Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas(UT) Southwestern-Children's Medical Center

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••