Hip implant under the microscope: tracking the avenir complete stem
NCT ID NCT04731077
First seen Oct 13, 2026 · Last updated Oct 14, 2026 · Updated 1 time
Summary
Researchers are following people who receive the Avenir Complete femoral stem during hip replacement surgery. The study enrolls adults with advanced hip joint damage from arthritis, injury, or previous failed hip surgery. It tracks how long the implant stays in place, any side effects, and how well patients move and function over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Avenir Complete femoral stem, a hip replacement implant
- What this could lead to
- If the implant performs well over time, it could give surgeons and patients more confidence in this option for hip replacement and revision surgery.
- What could go wrong
- This is a post-market follow-up study, not a randomized trial, so it cannot prove the implant is better than other stems. Some implants may loosen, wear, or need removal, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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275 people
The number who actually took part.
- Started
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Sep 2021
- Expected to finish
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Jun 2036
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient is at least 20 years old or older and skeletally mature. * Advanced wear of the joint due to degenerative, post-traumatic or rheumatic diseases; * Failed previous hip surgery including * Joint reconstruction (osteotomy) * Arthrodesis * Hemi-arthroplasty or total hip replacement (THR) * Acute traumatic fracture of the femoral head or neck; * Avascular necrosis of the femoral head. * Patients capable of understanding the surgeon's explanations and following his instructions, able and willing to participate in the follow-up program and who gave consent to take part in the study; Exclusion Criteria: * Acute, chronic, local, or systemic infections; * Severe muscular, neural, or vascular diseases that endanger the limbs involved; * Lack of bony structures proximal or distal to the joint, so that good Inclusion criteria * Patient is at least 20 years old or older and skeletally mature. * Advanced wear of the joint due to degenerative, post-traumatic or rheumatic diseases; * Failed previous hip surgery including * Joint reconstruction (osteotomy) * Arthrodesis * Hemi-arthroplasty or total hip replacement (THR) * Acute traumatic fracture of the femoral head or neck; * Avascular necrosis of the femoral head. * Patients capable of understanding the surgeon's explanations and following his instructions, able and willing to participate in the follow-up program and who gave consent to take part in the study; Exclusion criteria * Acute, chronic, local, or systemic infections; * Severe muscular, neural, or vascular diseases that endanger the limbs involved; * Lack of bony structures proximal or distal to the joint, so that good anchorage of the implant is unlikely or impossible; * Total or partial absence of the muscular or ligamentous apparatus; * Any concomitant diseases that can jeopardize the functioning and the success of the implant; * Allergy to the implanted material, especially to metal (e.g. cobalt, chromium, nickel, etc.); * Local bone tumors and/or cysts; * Pregnancy; * Skeletal immaturity. * Patients unwilling or unable to give consent, or to comply with the follow-up program; * Patients who have any condition that would - in the judgement of the Investigator - place him/her at undue risk or * interfere with the study; * Any vulnerable subject: * a prisoner * mentally incompetent or unable to understand what participation in the study entails * a known alcohol or drug abuser * anticipated to be non-compliant * Patients with plans to relocate during the study follow-up period; * Individuals whose willingness to volunteer in a clinical investigation could be unduly influenced by the expectation, whether justified or not, of benefits associated with participation or of retaliatory response from senior members of a hierarchy in case of refusal to participate;
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Copenhagen University Hospital, Hvidovre
Copenhagen, DK-2650, Denmark
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Heartland Regional Medical Center d.b.a. Mosaic Life Care
Saint Joseph, Missouri, 64506, United States
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Ikazia Ziekenhuis
Rotterdam, South Holland, 3083 AN, Netherlands
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Mississippi Sports Medicine and Orthopaedic Center PLLC
Jackson, Mississippi, 39202, United States
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Nissan Tamagawa Hospital
Setagaya-Ku, Tokyo, 410-0302, Japan
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Okayama City Hospital
Okayama, 700-0962, Japan
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Orthopedic & Fracture Clinic, PC
Portland, Oregon, 97225, United States
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Sahlgrenska University Hospital - Molndal
Mölndal, 43180, Sweden
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Sykehuset Innlandet HF
Tynset, 2500, Norway
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Sewing up a small hip tissue may curb Post-Surgery pain
- Robot arm aims to perfect hip implant angles
- Ten-Year watch on a hip implant: does the taperloc complete stem last?
- Can a cementless hip implant last? study tracks the SMS femoral stem
- Can a dual mobility hip implant outlast standard replacements?
- Can a computer guide hip surgeons to even out leg length?