Immunotherapy offers hope for young women with rare, Chemo-Resistant cancer

NCT ID NCT03135769

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called avelumab in 24 women with a rare pregnancy-related cancer (GTN) that did not respond to standard chemotherapy. The goal was to see if the drug could lower tumor markers (hCG) to normal levels and allow treatment to stop. Avelumab works by helping the immune system attack the cancer cells, offering a potentially less toxic option for these young patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aphp Hopital Tenon

    Paris, 75020, France

  • Centre Francois Baclesse

    Caen, 14000, France

  • Hospices Civils de Lyon - CHLS

    Pierre-Bénite, 69495, France

  • Institut Bergonie

    Bordeaux, 33000, France

  • Institut Paoli-Calmettes

    Marseille, 13000, France

  • Institut Universitaire Du Cancer de Toulouse - Oncopole

    Toulouse, 31000, France