New hope for kids with bleeding disorder: drug boosts platelets
NCT ID NCT04516967
First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 23 times
Summary
This study tested a medication called avatrombopag in 75 children aged 1 to 17 with immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing bleeding risks. The goal was to see if the drug could safely raise platelet counts to safer levels over 12 weeks. Participants received either the drug or a placebo, with an option to continue the drug in an open-label phase. The treatment aims to control the disease, not cure it, as ongoing management is needed.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Site 101
San Francisco, California, 94158, United States
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Site 102
Las Vegas, Nevada, 89135, United States
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Site 103
Long Beach, California, 90806, United States
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Site 104
Boston, Massachusetts, 02115, United States
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Site 105
Minneapolis, Minnesota, 55404, United States
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Site 106
Columbus, Ohio, 43205, United States
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Site 107
Peoria, Illinois, 61615, United States
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Site 108
Morristown, New Jersey, 07960, United States
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Site 109
Sacramento, California, 95817, United States
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Site 110
Providence, Rhode Island, 02903, United States
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Site 111
Aurora, Colorado, 80045, United States
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Site 112
Phoenix, Arizona, 85016, United States
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Site 113
Durham, North Carolina, 27710, United States
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Site 114
Jackson, Mississippi, 39216, United States
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Site 115
Houston, Texas, 77030, United States
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Site 116
Atlanta, Georgia, 30322, United States
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Site 117
Gainesville, Florida, 32610, United States
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Site 118
Charlotte, North Carolina, 28203, United States
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Site 119
Orange, California, 92868, United States
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Site 120
Wilmington, Delaware, 19803, United States
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Site 121
Philadelphia, Pennsylvania, 19104, United States
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Site 201
Toulouse, Occitanie, 31059, France
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Site 202
Paris, Île-de-France Region, 75019, France
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Site 301
Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
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Site 302
Hamburg, Free and Hanseatic City of Hamburg, 20246, Germany
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Site 303
Kiel, Schleswig-Holstein, 24105, Germany
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Site 304
Berlin, State of Berlin, 13353, Germany
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Site 401
Sheffield, England, S10 2TH, United Kingdom
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Site 402
Manchester, England, M13 9WL, United Kingdom
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Site 403
London, England, SE5 9RS, United Kingdom
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Site 405
Birmingham, England, B4 6NH, United Kingdom
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Site 406
Cardiff, Wales, CF14 4XW, United Kingdom
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Site 407
London, England, WC1N 3JH, United Kingdom
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Site 408
Liverpool, England, L12 2AP, United Kingdom
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Site 410
London, England, W12 0HS, United Kingdom
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Site 501
Olsztyn, Warmian-Masurian Voivodeship, 10-561, Poland
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Site 502
Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-667, Poland
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Site 503
Warsaw, Masovian Voivodeship, 02-091, Poland
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Site 504
Lodz, Łódź Voivodeship, 91-738, Poland
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Site 505
Zabrze, Silesian Voivodeship, 41-800, Poland
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Site 701
Adana, 01330, Turkey (Türkiye)
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Site 702
Antalya, 07160, Turkey (Türkiye)
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Site 703
Istanbul, 34764, Turkey (Türkiye)
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Site 704
Ankara, 06230, Turkey (Türkiye)
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Site 705
Denizli, 20160, Turkey (Türkiye)
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Site 706
Antalya, 07059, Turkey (Türkiye)
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Site 707
Izmir, 35100, Turkey (Türkiye)
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Site 708
Mersin, 33110, Turkey (Türkiye)
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Site 709
Istanbul, 34093, Turkey (Türkiye)
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Site 710
Istanbul, 34093, Turkey (Türkiye)
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Site 801
Budapest, 1094, Hungary
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Site 802
Miskolc, 3526, Hungary
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Site 803
Pécs, 7623, Hungary
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Site 901
Moscow, 119049, Russia
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Site 902
Nizhny Novgorod, 603136, Russia
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Site 903
Volgograd, 400138, Russia
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Site 904
Moscow, 117198, Russia
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Site 905
Saint Petersburg, 197022, Russia
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Site 906
Moscow, 117997, Russia
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Site 907
Chelyabinsk, 454076, Russia
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Site 952
Vinnytsia, 21029, Ukraine
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Site 954
Kharkiv, Kharkivs’ka Oblast’, 61000, Ukraine
Conditions
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