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Autopsies vs. clinical diagnoses: what are we missing in the ICU?

NCT ID NCT07769801

Knowledge-focused Sponsor: Central Hospital, Nancy, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time

Summary

This study looks back at patients who died in intensive care units and had an autopsy to see if the clinical diagnosis matched what the autopsy revealed. By comparing the two, researchers hope to find where major diagnostic errors occurred and how they might have affected patient care. The goal is to understand the true value of autopsies in improving future treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could reveal common diagnostic errors in intensive care, potentially guiding better treatment strategies and reaffirming the value of autopsies.
What could go wrong
This is a small, observational study, so findings may not apply broadly. Also, autopsies are rare, which could limit the data.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

32 people

The number who actually took part.

Started

May 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Systematic recruitment of all patients who died since 2008 at the Nancy University Hospital and the Metz-Thionville Regional Hospital, who had been hospitalized in an intensive care unit and underwent a medico-scientific autopsy.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion of all adult patients who died since 2008 in a department of the Metz-Thionville Regional Hospital or the Nancy University Hospital, who had been admitted to an intensive care unit during the same hospital stay, and who underwent a medico-scientific autopsy followed by an anatomopathological analysis. Exclusion Criteria: * Minor patients * Patients who were not admitted to intensive care * Forensic autopsies

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autopsy Autopsy in intensive care unit

Contacts and locations

Locations

  • Central Hospital, Nancy, France

    Nancy, France