Promising combo for stomach cancer stalls: trial ends early
NCT ID NCT07040059
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early-stage trial tested a new drug called AUR103 calcium, given together with standard treatments (trastuzumab and chemotherapy), for people with advanced HER2-positive stomach or gastroesophageal junction cancer. The study aimed to find a safe dose and check if the combination could shrink tumors. However, the trial was stopped early after enrolling only 2 participants, so we have very little information about how well it works or its safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AUR103 calcium (given with trastuzumab and chemotherapy drugs capecitabine and oxaliplatin)
- What this could lead to
- If it worked, this could point toward a new combination treatment for advanced HER2-positive stomach cancer.
- What could go wrong
- The trial was terminated early with only 2 participants, so we have very little data. It is too early to know if this combination is safe or effective.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Asha Hospital and Research Centre
Bangalore, Karnataka, 560076, India
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HCG Cancer Center
Vizag, Andhra Pradesh, 530040, India
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Hope & Heal Cancer Hospital and Research Center
Siliguri, West Bengal, 734015, India
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Karnataka Cancer Hospital and Radiation Theraphy Center
Bangalore, Karnataka, 560096, India
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Kiran Hospital Multi Super Speciality Hospital & Reseach Center
Surat, Gujarat, 395004, India
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Netaji Subhas Chandra Bose Cancer Hospital
Kolkata, West Bengal, 700094, India
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Shalby Hospital
Ahmedabad, Gujarat, 380015, India
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The Gujarat Cancer & Research Insititute
Ahmedabad, Gujarat, 380016, India
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can AI-Guided home training boost recovery from gastric cancer surgery?
- Can a new drug combo shrink Hard-to-Treat tumors?
- Can an immunotherapy combo shrink stomach tumors before surgery?
- Can adding immunotherapy to chemotherapy improve gastric cancer outcomes?
- Can a smart drug home in on Hard-to-Treat cancers?
- Could a smartphone program supervised by AI boost recovery after stomach cancer surgery?