New registry aims to uncover why some osteoporosis patients get rare fractures

NCT ID NCT01747291

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is building a registry of 300 people in Ontario who have had a rare type of thigh bone fracture called an atypical femur fracture. Researchers want to learn more about what causes these fractures, which have been linked to long-term use of osteoporosis drugs called bisphosphonates. By collecting detailed information from patients, they hope to identify risk factors and improve prevention.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could identify risk factors and predictors for atypical femur fractures, helping doctors prevent them in the future.
What could go wrong
This is an observational registry, not a treatment trial. It may not find clear causes or lead to immediate changes in care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • McMaster University

    ENROLLING_BY_INVITATION

    Hamilton, Ontario, Canada

  • St Michael's Hospital

    ENROLLING_BY_INVITATION

    Toronto, Ontario, Canada

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

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