New drug trial aims to ease debilitating muscle stiffness

NCT ID NCT06300307

Summary

This early-stage trial is testing a new drug called ATX-01 in adults with myotonic dystrophy type 1 (DM1), a genetic disorder that causes progressive muscle weakness and stiffness. The main goal is to see if the drug is safe and well-tolerated when given as a single dose or as three doses. Researchers will also check if it helps improve symptoms like hand stiffness and leg strength, which could help with daily activities.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Intégré Universitaire de Santé et Services Sociaux du Saguenay-Lac-St-Jean

    RECRUITING

    Chicoutimi, Quebec, G7H 5H6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione Policlinico A. Gemelli- IRCCS

    RECRUITING

    Rome, 00168, Italy

    Contact Email: •••••@•••••

  • Hospital Universitario Donostia

    RECRUITING

    Donostia / San Sebastian, 20014, Spain

    Contact

    Contact Email: •••••@•••••

  • Institute of Myology

    RECRUITING

    Paris, 75651, France

    Contact Email: •••••@•••••

  • Radboudumc

    RECRUITING

    Nijmegen, 6525, Netherlands

    Contact

    Contact Email: •••••@•••••

  • St. George's University Hospital

    RECRUITING

    London, SW17 0RE, United Kingdom

    Contact

    Contact Email: •••••@•••••

  • The NeMO Clinical Center in Milan, Neurorehabilitation Unit, University of Milan

    RECRUITING

    Milan, 20162, Italy

    Contact Email: •••••@•••••

  • UCLA

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Florida

    RECRUITING

    Gainesville, Florida, 32610, United States

    Contact Email: •••••@•••••

  • University of Iowa Health Care - Department of Neurology

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kansas Medical Center, Department of Neurology

    RECRUITING

    Fairway, Kansas, 66205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.