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New pill may help adults with rare adrenal disorder cut back on steroids

NCT ID NCT07144163

Recruiting now Disease control Sponsor: Crinetics Pharmaceuticals Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug, atumelnant, in 150 adults with classic congenital adrenal hyperplasia (CAH). The goal is to see if it can safely control hormone levels and allow patients to take lower doses of their usual steroid medications. Participants will receive either atumelnant or a placebo, and researchers will monitor hormone levels and side effects over time.

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Conditions

The condition(s) this trial relates to.

classic congenital adrenal hyperplasia classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency congenital adrenal hyperplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLASSIC CONGENITAL ADRENAL HYPERPLASIA CONGENITAL ADRENAL HYPERPLASIA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Crinetics Study Site

    RECRUITING

    Los Angeles, California, 90027, United States

  • Crinetics Study Site

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Crinetics Study Site

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Crinetics Study Site

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • Crinetics Study Site

    RECRUITING

    Minneapolis, Minnesota, 55417, United States

  • Crinetics Study Site

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Crinetics Study Site

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

  • Crinetics Study Site

    RECRUITING

    Dallas, Texas, 75390, United States

  • Crinetics Study Site

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Crinetics Study Site

    RECRUITING

    Buenos Aires, Buenos Aires F.D., 1405, Argentina

  • Crinetics Study Site

    RECRUITING

    Buenos Aires, Buenos Aires F.D., C1012AAR, Argentina

  • Crinetics Study Site

    RECRUITING

    CABA, Buenos Aires F.D., C1199ABB, Argentina

  • Crinetics Study Site

    RECRUITING

    Córdoba, Córdoba Province, X5000JRD, Argentina

  • Crinetics Study Site

    RECRUITING

    Herston, Queensland, 4029, Australia

  • Crinetics Study Site

    RECRUITING

    Woolloongabba, Queensland, 4102, Australia

  • Crinetics Study Site

    RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Crinetics Study Site

    RECRUITING

    Parkville, Victoria, 3050, Australia

  • Crinetics Study Site

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

  • Crinetics Study Site

    RECRUITING

    Vienna, 1090, Austria

  • Crinetics Study Site

    RECRUITING

    Curitiba, Paraná, 33172, Brazil

  • Crinetics Study Site

    RECRUITING

    Rio de Janeiro, Rio de Janeiro, 20231-092, Brazil

  • Crinetics Study Site

    RECRUITING

    Rio de Janeiro, Rio de Janeiro, 20551-030, Brazil

  • Crinetics Study Site

    RECRUITING

    Botucatu, São Paulo, 18618-686, Brazil

  • Crinetics Study Site

    RECRUITING

    São Paulo, São Paulo, 04024-002, Brazil

  • Crinetics Study Site

    RECRUITING

    São Paulo, São Paulo, 05403-000, Brazil

  • Crinetics Study Site

    RECRUITING

    Angers, 49933, France

  • Crinetics Study Site

    RECRUITING

    Bron, 69500, France

  • Crinetics Study Site

    RECRUITING

    Nantes, 44093 Cedex 1, France

  • Crinetics Study Site

    RECRUITING

    Paris, 75013, France

  • Crinetics Study Site

    RECRUITING

    Pessac, 33604, France

  • Crinetics Study Site

    RECRUITING

    Vandœuvre-lès-Nancy, 54500, France

  • Crinetics Study Site

    RECRUITING

    Munich, Bavaria, 80336, Germany

  • Crinetics Study Site

    RECRUITING

    Würzburg, 97080, Germany

  • Crinetics Study Site

    RECRUITING

    Milan, Milano, 20149, Italy

  • Crinetics Study Site

    RECRUITING

    Rozzano, Milano, 20089, Italy

  • Crinetics Study Site

    RECRUITING

    Padova, Padova, 35128, Italy

  • Crinetics Study Site

    RECRUITING

    Palermo, Palermo, 90127, Italy

  • Crinetics Study Site

    RECRUITING

    Naples, 80131, Italy

  • Crinetics Study Site

    RECRUITING

    Roma, 00161, Italy

  • Crinetics Study Site

    RECRUITING

    Warsaw, Masovian Voivodeship, 00-189, Poland

  • Crinetics Study Site

    RECRUITING

    Lodz, Łódź Voivodeship, 93-338, Poland

  • Crinetics Study Site

    RECRUITING

    Gothenburg, 413 46, Sweden

  • Crinetics Study Site

    RECRUITING

    Stockholm, 171 76, Sweden

  • Crinetics Study Site

    RECRUITING

    London, NW1 2PG, United Kingdom

  • Crinetics Study Site

    RECRUITING

    Manchester, M20 4BX, United Kingdom