Heart ablation showdown: which technique stops fainting best?

NCT ID NCT07162740

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests two heart ablation methods—right atrial only vs. bi-atrial—to see which better prevents fainting caused by reflex syncope. Fifty adults aged 18–60 with severe, recurrent fainting will be monitored with an implantable loop recorder. The goal is to find the most effective and safe technique to reduce asystolic episodes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cardioneuroablation (a procedure that uses heat to disable nerve clusters in the heart)
What this could lead to
If successful, this study could identify the best ablation technique to reduce or prevent fainting spells in people with reflex syncope.
What could go wrong
This is a small, early-stage study (50 people) comparing two existing procedures, so results may not apply broadly. Ablation carries risks like bleeding, infection, or heart rhythm issues.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS Istituto Auxologico Italiano

    Milan, 20149, Italy

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