Scientists map Eczema's genetic fingerprint in skin
NCT ID NCT05436535
Summary
This study aimed to understand the different genetic patterns, or 'endotypes,' in the skin of people with mild versus moderate-to-severe eczema (atopic dermatitis). Researchers collected skin samples from 433 participants, including people with eczema and those without, over multiple visits to see how these patterns change with standard treatments like topical steroids or dupilumab. The goal was to gather detailed biological knowledge to potentially guide future, more personalized treatments.
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Contacts and locations
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Locations
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Boston Children's Hospital: Department of Immunology
Boston, Massachusetts, 02215, United States
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Children's Hospital Los Angeles: Division of Clinical Immunology & Allergy
Los Angeles, California, 90027, United States
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Cincinnati Children's Hospital Medical Center: Asthma Center
Cincinnati, Ohio, 45229, United States
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Icahn School of Medicine at Mount Sinai: Department of Pediatrics Allergy & Immunology
New York, New York, 10029, United States
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National Jewish Health: Division of Pediatric Allergy and Clinical Immunology
Denver, Colorado, 80206, United States
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North Carolina Children's Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology
Chapel Hill, North Carolina, 27599, United States
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Oregon Health & Science University: Department of Dermatology
Portland, Oregon, 97239, United States
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University of California, San Diego: Dermatology Clinical Trials Unit
La Jolla, California, 92093, United States
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University of Pennsylvania, Perelman Center for Advanced Medicine: Department of Dermatology
Philadelphia, Pennsylvania, 19104, United States
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University of Rochester Medical Center: Department of Dermatology
Rochester, New York, 14642, United States
Conditions
Explore the condition pages connected to this study.