5,000-Person study aims to take guesswork out of depression treatment

NCT ID NCT07528014

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will collect data from 5,000 adults with depressed mood who are receiving esketamine, TMS, or SAINT therapy in routine care. Researchers will analyze this information to build models that could one day predict which treatment is most likely to help a given patient. The goal is to move toward more personalized depression care, but the study itself does not test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to tools that help doctors choose the best depression treatment for each person, improving outcomes.

What could go wrong

This is an observational study, not a treatment trial. The predictive models may not prove accurate enough for real-world use, and results may take years to develop.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Consciousness Disorders Depression Depressive Disorder, Treatment-Resistant major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Salma Health

    RECRUITING

    La Jolla, California, 92037, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Salma Health

    RECRUITING

    Laguna Hills, California, 92653, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••