New drug combo shows promise for aggressive stomach cancer

NCT ID NCT04661150

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 29 times

Summary

This study tests whether adding the immunotherapy drug atezolizumab to standard chemotherapy and trastuzumab can improve outcomes for people with HER2-positive stomach or gastroesophageal junction cancer that can be surgically removed. About 42 participants will receive either the standard treatment or the standard plus atezolizumab before and after surgery. The main goal is to see if the combination leads to a complete disappearance of cancer cells in the removed tissue.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, 100142, China

  • First Hospital of China Medical University

    Shenyang, 110001, China

  • Harbin Medical University Cancer Hospital

    Harbin, 150081, China

  • Liaoning Provincial Cancer Hospital

    Shengyang, 110042, China

  • Nanfang Hospital, Southern Medical University

    Guangzhou, 510515, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjing, 300060, China

  • West China Hospital, Sichuan University

    Chengdu, 610041, China

  • Zhongshan Hospital Fudan University

    Shanghai, 200032, China

Conditions

Explore the condition pages connected to this study.