New combo aims to wipe out stomach cancer before surgery

NCT ID NCT04661150

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 21 times

Summary

This study tests whether adding an immunotherapy drug (atezolizumab) to standard chemotherapy and targeted therapy (trastuzumab) can better shrink HER2-positive stomach or gastroesophageal junction cancer before surgery. About 42 adults with advanced but removable tumors will receive the combo or standard treatment. The main goal is to see if the cancer completely disappears in the removed tissue.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, 100142, China

  • First Hospital of China Medical University

    Shenyang, 110001, China

  • Harbin Medical University Cancer Hospital

    Harbin, 150081, China

  • Liaoning Provincial Cancer Hospital

    Shengyang, 110042, China

  • Nanfang Hospital, Southern Medical University

    Guangzhou, 510515, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjing, 300060, China

  • West China Hospital, Sichuan University

    Chengdu, 610041, China

  • Zhongshan Hospital Fudan University

    Shanghai, 200032, China

Conditions

Explore the condition pages connected to this study.