New drug cocktail targets breast cancer brain metastases

NCT ID NCT03417544

First seen May 17, 2026 ยท Last updated May 17, 2026

Summary

This study tested a combination of three drugs (atezolizumab, pertuzumab, and high-dose trastuzumab) in 19 people with HER2-positive breast cancer that had spread to the brain. The goal was to see if the treatment could shrink or control brain tumors. The approach aims to improve outcomes for a hard-to-treat condition, but ongoing management is still needed.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

Conditions

Explore the condition pages connected to this study.