Can an immune booster before surgery beat lung cancer?

NCT ID NCT02994576

First seen Aug 17, 2026 ยท Last updated Aug 17, 2026

Summary

This trial is testing whether giving the immunotherapy drug atezolizumab before surgery can help people with early-stage non-small cell lung cancer. The study includes adults with stage IB to IIIA (non-N2) disease who are eligible for surgery. Participants receive one dose of atezolizumab, then undergo surgery, and the trial tracks safety and how well the treatment works.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
atezolizumab (an immunotherapy drug given by IV infusion before surgery)
What this could lead to
If it works, giving atezolizumab before surgery could shrink tumors and improve outcomes for people with early-stage lung cancer, potentially leading to a new treatment approach.
What could go wrong
This is a small, early-phase study, so results may not be conclusive. The drug can cause immune-related side effects, and surgery delays or complications are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier de Chauny

    Chauny, France

  • Centre Marie Lannelongue

    Le Plessis-Robinson, France

  • Gustave Roussy

    Villejuif, Val de Marne, 94805, France

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