Can a new drug tame hepatitis e? a first human trial begins

NCT ID NCT07728487

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This early-stage trial tests an experimental drug called AT-587 in healthy adults to see if it is safe and how the body processes it. The drug is being developed as a potential treatment for hepatitis E, a liver infection that currently has no approved therapy. Participants receive either AT-587 or a placebo, and researchers monitor for side effects and measure drug levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an experimental drug called AT-587
What this could lead to
If safe and effective, AT-587 could become a treatment option for hepatitis E, a liver infection with no approved therapy.
What could go wrong
This is a very early Phase 1 trial in healthy people, so it does not yet test whether the drug works against the virus. Side effects may emerge.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Atea Study Site

    RECRUITING

    Edegem, 2650, Belgium

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Other studies related to the condition(s) this trial covers.