Early trial tests new drug combo for aggressive brain cancers

NCT ID NCT03922555

Summary

This early-stage study is testing the safety and highest tolerable dose of a two-drug combination called ASTX727 for adults with recurrent IDH-mutant brain tumors that have started growing again. The trial will enroll 18 participants to determine how much medication can be given safely while monitoring for side effects. Researchers hope this combination may help control tumor growth in these difficult-to-treat cancers.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Email: •••••@•••••

    Contact

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Email: •••••@•••••

    Contact

  • Massachusetts General Hospital Cancer Center

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.