New hope for hard-to-treat merkel cell cancer: drug combo aims to shrink tumors
NCT ID NCT07472322
First seen Mar 27, 2026 · Last updated May 11, 2026 · Updated 5 times
Summary
This study tests whether combining two drugs—ASTX727 (a pill) and retifanlimab (given through a vein)—can shrink tumors and slow cancer growth in people with advanced Merkel cell cancer that no longer responds to standard immunotherapy. About 31 adults will receive the treatment for up to 2 years, with clinic visits every 2 weeks. The main goals are to check safety and see if the combination works better than current options.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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University of Wisconsin-Carbone Cancer Center
Madison, Wisconsin, 53792, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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