New pill targets Cancer's survival system in patients out of options

NCT ID NCT02503423

Summary

This study is testing a new oral drug called ASTX660 in adults with advanced solid tumors or lymphoma that have stopped responding to standard treatments. The main goals are to find the safest and most effective dose and to see if the drug can help control the cancer. The trial is for patients who have no other life-prolonging treatments available.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Azienda Ospedaliero-Universitaria di Bologna Policlinico Sant Orsola-Malpighi

    Bologna, 40138, Italy

  • Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

    Brescia, 25123, Italy

  • Azienda Socio Santaria Territoriale Monza- Osperdale San Gerado

    Monza, Italy

  • Beatson Cancer Center and University of Glasgow

    Glasgow, G12 0XL, United Kingdom

  • British Columbia Cancer Agency

    Vancouver, British Columbia, V5Z 4E6, Canada

  • CRU de Tours - Hôpital Bretonneau, Hématologie -Thérapy Cellulaire

    Tours, 37044, France

  • Cancer Care Manitoba

    Winnipeg, Manitoba, R3E 0V9, Canada

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Centre Antoine Lacassagne, Oncologie Médicale

    Nice, 06189, France

  • Centre Henri Becquerel, Hematology

    Rouen, 1,76-38, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, Lyon, 69310, France

  • Centre Hospitalier Universitaire Universite Catholique de Louvain - Site Godinne

    Yvoir, Namur, B-5530, Belgium

  • Churchill Hospital, Oxford University Hospital NHS Trust

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

  • CliniCore Texas

    Houston, Texas, 77079, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Dartmouth-Hitchcock Medical Center (DHMC)

    Lebanon, New Hampshire, 03766, United States

  • Debreceni Egyetem Klinikai Központ

    Debrecen, 4032, Hungary

  • Emory University winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Gustave Roussy Cancer Campus (IGR)

    Villejuif, Cedex, 94805, France

  • Guy's and Saint Thomas' NHS Foundation Trust

    London, SE1 9RT, United Kingdom

  • Hollings Cancer Center

    Charleston, South Carolina, 29425, United States

  • HonorHealth Research Institute

    Scottsdale, Arizona, 852558, United States

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Fundacion Jimenez Diaz Preview

    Madrid, 28040, Spain

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Institut Bergonié, Unicancer

    Bordeaux, 33000, France

  • Institut Catala d'Oncologia

    Girona, Giona, Spain

  • Institut Universitaire du Cancer - Oncopôle, Department d'Hématologie

    Toulouse, 31059, France

  • Instituto Europeo di Oncologia

    Milan, Italy

  • Intitut Jules Boredt

    Brussels, 1000, Belgium

  • Jewish General Hospital

    Montreal, Quebec, H3T 1E2, Canada

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • New York Presbyterian Hospital Columbia University Medical Center

    New York, New York, 10019, United States

  • New York University Langone Medical Center

    New York, New York, 10016, United States

  • Nova Scotia Health Athority-Qeii HSC

    Halifax, Nova Scotia, B3H 2Y9, Canada

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M56 2M9, Canada

  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University

    Chicago, Illinois, 60611, United States

  • Rochester Skin Lymphoma Medical Group

    Rochester, New York, 14450, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • START- South Texas Accelerated Research Therapeutics

    San Antonio, Texas, 78229, United States

  • Semmelweis Egyetem - I. sz. Belgyógyászati Klinika

    Budapest, 1083, Hungary

  • Simlow Cancer Hospital at Yale

    New Haven, Connecticut, 06510, United States

  • Summit Medical Group - Florham Park Campus/Atlantic Health

    Florham Park, New Jersey, 07932, United States

  • Sunnybrook Hospital

    Toronto, Ontario, M4N 3M5, Canada

  • Szabolcs-Szatmár-Bereg Megyei Kórházak És Egyetemi Oktatókórház

    Nyíregyháza, Hungary

  • The Christie NHS Foundation Trust, Christie Hospital

    Manchester, M20 4BX, United Kingdom

  • The Ohio State University and Wexner Medical Center, James Cancer Hospital

    Columbus, Ohio, 43210, United States

  • The Royal Marsden NHS Foundation Trust

    Sutton, Surrey, SM2 5PT, United Kingdom

  • The Sidney Kimmel Comprehensive Cancer Center at John Hopkins

    Baltimore, Maryland, 21287, United States

  • Tom Baker Cancer Centre

    Calgary, Alberta, Canada

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • UC Davis Medical Center

    Sacramento, California, 95817, United States

  • USC/Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • Universitair Ziekenhuis Gent

    Ghent, Oost-Vlaanderen, 9000, Belgium

  • University College London Hospitals NHS Foundation Trust

    London, NW1 2PG, United Kingdom

  • University Hospital Southhampton NHS Foundation Trust - Somers Cancer Research

    Southampton, Hampshire, SO16 6YD, United Kingdom

  • University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital

    Birmingham, B15 2TH, United Kingdom

  • University Hospitals of Leicester NHS Trust

    Leicester, East Midlands, LE1 5WW, United Kingdom

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Oklahoma Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Washington, Seattle Cancer Care Alliance

    Seattle, Washington, 98109, United States

  • Vanderbilt Ingram Cancer Center

    Nashville, Tennessee, 37212, United States

  • Virgina Commonwealth University

    Richmond, Virginia, 23298, United States

  • Wake Forest Baptist Health

    Winston-Salem, North Carolina, 27157, United States

  • West Penn Hospital

    Pittsburgh, Pennsylvania, 15224, United States

  • imCORE - Clínica Universidad de Navarra

    Pamplona, Navarre, 31008, Spain

Conditions

Explore the condition pages connected to this study.