New combo aims to reignite immune attack on Hard-to-Treat breast cancer

NCT ID NCT07015853

First seen May 02, 2026 · Last updated May 16, 2026 · Updated 3 times

Summary

This study tests whether adding radiation and a drug called axatilimab to the immunotherapy pembrolizumab can help shrink tumors in people with metastatic triple-negative breast cancer (TNBC) who have already tried immunotherapy. About 34 adults with at least two measurable tumors will receive the combination. One tumor will be radiated to try to spark a broader immune response against all tumors. The main goal is to see how many patients have their non-radiated tumors shrink or disappear.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

Conditions

Explore the condition pages connected to this study.