Spleenless patients under the microscope: can we predict their biggest health threats?

NCT ID NCT04199403

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study follows 6,000 adults in France who have had their spleen removed or rendered non-functional due to surgery, radiation, or embolization. Researchers aim to identify risk factors for serious complications such as infections, cancer, and blood clots. By comparing different causes of asplenia, the study hopes to improve long-term monitoring and care for these patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could lead to better monitoring guidelines and earlier detection of complications in people without a functioning spleen.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to all types of asplenia or to non-French populations.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • C.H. Victor Dupouy

    RECRUITING

    Argenteuil, 95100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • C.H. d'Angoulême

    RECRUITING

    Angoulême, 16959, France

    Contact Email: •••••@•••••

  • C.H. de Béthune

    WITHDRAWN

    Béthune, 62660, France

  • C.H. de Tourcoing

    RECRUITING

    Tourcoing, 59208, France

    Contact Email: •••••@•••••

  • C.H. de Valenciennes

    RECRUITING

    Valenciennes, 59300, France

    Contact Email: •••••@•••••

  • C.H.U. de Lille

    RECRUITING

    Lille, 59037, France

    Contact Email: •••••@•••••

  • C.H.U. de Montpellier

    RECRUITING

    Montpellier, 34295, France

    Contact Email: •••••@•••••

  • C.H.U. de Poitiers

    RECRUITING

    Poitiers, 86000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • C.H.U. de Rouen

    NOT_YET_RECRUITING

    Rouen, 76031, France

    Contact Email: •••••@•••••

  • C.H.U. de Toulouse

    RECRUITING

    Toulouse, 31059, France

    Contact Email: •••••@•••••

  • Hôpitaux de Chartres

    ACTIVE_NOT_RECRUITING

    Chartres, 28019, France

  • Hôtel-Dieu - CHU de Nantes

    RECRUITING

    Nantes, 44093, France

    Contact Email: •••••@•••••

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