Heart valve patients may ditch blood thinners for simple aspirin

NCT ID NCT07431762

Recruiting now Disease control Sponsor: Asan Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study compares aspirin to the blood thinner warfarin in 1058 people who just had a bioprosthetic heart valve replacement. For 6 months after surgery, participants take either daily aspirin or warfarin. The goal is to see if aspirin is just as safe and effective at preventing blood clots, strokes, and other complications, potentially offering a simpler treatment option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: aspirin or warfarin
What this could lead to: If aspirin works as well as warfarin, patients could avoid the frequent blood tests and dietary restrictions needed with warfarin.
What could go wrong: This is a phase 4 trial, so the drugs are already approved, but it's still possible that aspirin is less effective at preventing clots, which could increase stroke risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEART VALVE DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

heart valve disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VALVE REPLACEMENT SURGERY

Contacts and locations

Locations

Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
National Cerebral and Cardiovascular Center Hospital
NOT_YET_RECRUITING

Osaka, 564-8565, Japan
Osaka University Hospital
NOT_YET_RECRUITING

Osaka, 565-0871, Japan

More trials for these conditions

Other studies related to the condition(s) this trial covers.