Blood thinner showdown: aspirin vs warfarin after valve surgery

NCT ID NCT07431762

First seen Mar 03, 2026 · Last updated May 15, 2026 · Updated 6 times

Summary

This study compares two blood-thinning medicines, aspirin and warfarin, to see which is safer for preventing clots in the first 6 months after a tissue heart valve replacement. About 1,058 adults who had aortic or mitral valve surgery will be randomly assigned to one of the two treatments. The goal is to find the best way to manage clot risk without causing excess bleeding.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

    Contact

  • National Cerebral and Cardiovascular Center Hospital

    Osaka, 564-8565, Japan

    Contact

  • Osaka University Hospital

    Osaka, 565-0871, Japan

    Contact

Conditions

Explore the condition pages connected to this study.