Gene therapy hope for toddlers with rare brain disorder

NCT ID NCT07480564

First seen Mar 21, 2026 · Last updated May 11, 2026 · Updated 8 times

Summary

This study tests a single dose of a gene therapy called TSHA-102 in 3 girls aged 2 to 4 with Rett syndrome, a severe genetic disorder. The therapy is given as a spinal injection and aims to improve symptoms by delivering a working copy of the faulty gene. The main goal is to check safety and see if it helps control the disease.

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Contacts and locations

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Conditions

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