Gene therapy hope for toddlers with rare brain disorder

NCT ID NCT07480564

First seen Mar 21, 2026 · Last updated May 25, 2026 · Updated 11 times

Summary

This study tests a one-time gene therapy called TSHA-102 in girls aged 2 to 4 with Rett syndrome, a severe genetic brain disorder. The treatment is given as a single injection into the spinal fluid. The goal is to see if it is safe and if it can improve symptoms. Only 3 participants will be enrolled in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.