New drug targets tough cancers with KRAS G12D mutation

NCT ID NCT07483983

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called ASP3082 in 60 people with advanced lung or pancreatic cancer that has a specific gene change (KRAS G12D). Participants receive the drug intravenously once a week in 21-day cycles. The main goal is to see how well the drug shrinks tumors and to understand why some cancers stop responding.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Neoplasm Metastasis non-small cell lung carcinoma pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Georges François Leclerc

    NOT_YET_RECRUITING

    Dijon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gustave Roussy

    RECRUITING

    Villejuif, France, 94800, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Bergonié

    NOT_YET_RECRUITING

    Bordeaux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Paoli Calmettes

    NOT_YET_RECRUITING

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de Lorraine

    NOT_YET_RECRUITING

    Vandœuvre-lès-Nancy, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de l'Ouest

    NOT_YET_RECRUITING

    Saint-Herblain, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••