Light-Activated drug combo shows promise in fighting head and neck cancer
NCT ID NCT06699212
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 30 times
Summary
This study tests a new treatment called ASP-1929 photoimmunotherapy, which uses light to activate a drug that targets cancer cells, combined with the immunotherapy pembrolizumab. It is for people with head and neck cancer that has come back in the same area but has not spread to other parts of the body. The goal is to see if this combination helps people live longer compared to standard treatments like pembrolizumab alone or with chemotherapy.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Aichi Cancer Center
RECRUITINGAichi, 464-8681, Japan
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Avera Cancer Institute
RECRUITINGSioux Falls, South Dakota, 57105, United States
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Chi Mei Hospital
RECRUITINGTainan, 736402, Taiwan
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China Medical University
RECRUITINGTaichung, 404327, Taiwan
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City of Hope
RECRUITINGDuarte, California, 91010, United States
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Hiroshima University Hospital
RECRUITINGHiroshima, 734-8551, Japan
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Kaohsiung Medical University Chung-Ho Memorial Hospital
RECRUITINGKaohsiung City, 807377, Taiwan
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Kyoto Prefectural University of Medicine
RECRUITINGKyoto, 602-8566, Japan
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Linkou Chang Gung Memorial Hospital
RECRUITINGTaoyuan City, 333423, Taiwan
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MacKay Memorial Hospital
RECRUITINGTaipei, 104217, Taiwan
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National Taiwan University Hospital
RECRUITINGTaipei, 100225, Taiwan
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Rhode Island Hospital
RECRUITINGProvidence, Rhode Island, 02903, United States
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Taichung Veterans General Hospital
RECRUITINGTaichung, 407219, Taiwan
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Taipei Municipal Wanfang Hospital
RECRUITINGTaipei, 116081, Taiwan
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Taipei Veterans General Hospital
RECRUITINGTaipei, 112201, Taiwan
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Tampa General Hospital
RECRUITINGTampa, Florida, 33606, United States
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Thomas Jefferson University, Sidney Kimmel Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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Tokyo Medical University Hospital
RECRUITINGTokyo, 160-0023, Japan
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Tottori University Hospital
RECRUITINGYonago, 683-8504, Japan
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University of Kentucky Medical Center
WITHDRAWNLexington, Kentucky, 40536, United States
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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University of Texas, MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Conditions
Explore the condition pages connected to this study.