New hope for leukemia patients: asciminib shows promise in indian study

NCT ID NCT06427811

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at the safety and effectiveness of a drug called asciminib in 85 Indian adults with a specific type of leukemia (Ph+ CML-CP). Some participants had a genetic mutation (T315I) that can make treatment harder, while others had already tried two or more other drugs. The goal was to confirm that asciminib works and is safe for these patients, as part of a post-approval requirement by Indian health authorities.

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome chronic myelogenous leukemia, BCR-ABL1 positive Leukemia, Myelogenous, Chronic, BCR-ABL Positive

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Novartis Investigative Site

    Ahmedabad, Gujarat, 380009, India

  • Novartis Investigative Site

    Ahmedabad, Gujarat, 382428, India

  • Novartis Investigative Site

    Bengaluru, Karnataka, 560034, India

  • Novartis Investigative Site

    Trivandrum, Kerala, 695 011, India

  • Novartis Investigative Site

    Pune, Maharashtra, 422001, India

  • Novartis Investigative Site

    New Delhi, National Capital Territory of Delhi, 431005, India

  • Novartis Investigative Site

    Hyderabad, Telangana, 500082, India

  • Novartis Investigative Site

    Kolkata, West Bengal, 700014, India

  • Novartis Investigative Site

    Cuttack, 753007, India

  • Novartis Investigative Site

    Guwahati, 781003, India