New hope for advanced breast cancer: experimental drug targets tumors after other treatments fail

NCT ID NCT04829604

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests an experimental drug called ARX788 in people with HER2-positive breast cancer that has spread and no longer responds to standard treatments. About 72 adults will receive the drug to see if it shrinks tumors and how long that effect lasts. The goal is to find a new option for controlling the disease when other therapies stop working.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast neoplasm HER2 positive breast carcinoma Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Los Angeles, California, 90033, United States

  • Research Site

    Newport Beach, California, 92663, United States

  • Research Site

    San Francisco, California, 94158, United States

  • Research Site

    Whittier, California, 90602, United States

  • Research Site

    Atlanta, Georgia, 30322, United States

  • Research Site

    Chicago, Illinois, 60611, United States

  • Research Site

    Louisville, Kentucky, 40207, United States

  • Research Site

    Silver Spring, Maryland, 20904, United States

  • Research Site

    Boston, Massachusetts, 02215, United States

  • Research Site

    St Louis, Missouri, 63110, United States

  • Research Site

    Omaha, Nebraska, 68130, United States

  • Research Site

    Las Vegas, Nevada, 89128, United States

  • Research Site

    Camden, New Jersey, 08103, United States

  • Research Site

    New Hyde Park, New York, 11042, United States

  • Research Site

    New York, New York, 10028, United States

  • Research Site

    Shirley, New York, 11967, United States

  • Research Site

    The Bronx, New York, 10469, United States

  • Research Site

    Portland, Oregon, 97213, United States

  • Research Site

    Tigard, Oregon, 97223, United States

  • Research Site

    Philadelphia, Pennsylvania, 19104, United States

  • Research Site

    Dallas, Texas, 75246, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    San Antonio, Texas, 78229, United States

  • Research Site

    Norfolk, Virginia, 23502, United States

  • Research Site

    Tacoma, Washington, 98405, United States

  • Research Site

    Frankston, Victoria, 3199, Australia

  • Research Site

    Geelong, Victoria, 3220, Australia

  • Research Site

    Nedlands, Western Australia, 6009, Australia

  • Research Site

    Daegu, 42601, South Korea

  • Research Site

    Seongnam-si, 13620, South Korea

  • Research Site

    Seoul, 02841, South Korea

  • Research Site

    Seoul, 03722, South Korea

  • Research Site

    Seoul, 05505, South Korea