New hope for advanced breast cancer patients who stopped responding to standard therapy
NCT ID NCT04829604
First seen Nov 16, 2025 · Last updated May 15, 2026 · Updated 17 times
Summary
This phase 2 study tests a new drug called ARX788 in 72 adults with HER2-positive metastatic breast cancer that has spread and is not removable by surgery. Participants must have already been treated with a specific prior therapy (T-DXd) and up to 5 total prior treatments. The main goal is to see how many patients' tumors shrink or disappear, and how long that effect lasts.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Research Site
Los Angeles, California, 90033, United States
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Research Site
Newport Beach, California, 92663, United States
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San Francisco, California, 94158, United States
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Research Site
Whittier, California, 90602, United States
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Atlanta, Georgia, 30322, United States
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Chicago, Illinois, 60611, United States
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Louisville, Kentucky, 40207, United States
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Silver Spring, Maryland, 20904, United States
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Boston, Massachusetts, 02215, United States
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St Louis, Missouri, 63110, United States
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Omaha, Nebraska, 68130, United States
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Las Vegas, Nevada, 89128, United States
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Camden, New Jersey, 08103, United States
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New Hyde Park, New York, 11042, United States
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New York, New York, 10028, United States
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Shirley, New York, 11967, United States
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The Bronx, New York, 10469, United States
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Portland, Oregon, 97213, United States
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Tigard, Oregon, 97223, United States
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Philadelphia, Pennsylvania, 19104, United States
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Dallas, Texas, 75246, United States
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Houston, Texas, 77030, United States
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San Antonio, Texas, 78229, United States
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Norfolk, Virginia, 23502, United States
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Tacoma, Washington, 98405, United States
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Frankston, Victoria, 3199, Australia
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Geelong, Victoria, 3220, Australia
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Research Site
Nedlands, Western Australia, 6009, Australia
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Research Site
Daegu, 42601, South Korea
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Research Site
Seongnam-si, 13620, South Korea
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Research Site
Seoul, 02841, South Korea
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Research Site
Seoul, 03722, South Korea
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Research Site
Seoul, 05505, South Korea
Conditions
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