New device aims to seal brain aneurysms without open surgery

NCT ID NCT02998229

Recruiting now Disease control Sponsor: Medtronic Neurovascular Clinical Affairs Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 4 times

Summary

This study tests a device called Artisse, which is placed inside a brain aneurysm to block blood flow and prevent rupture. It involves 300 people aged 18-75 with wide-neck aneurysms that are either unruptured or recently ruptured. The main goal is to see if the device safely and effectively seals the aneurysm within one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Artisse™ Intrasaccular Device (a device placed inside the aneurysm to block blood flow)
What this could lead to: If successful, this device could offer a new, less invasive way to treat wide-neck brain aneurysms, potentially reducing the risk of rupture or rebleeding.
What could go wrong: This is an early-stage study with 300 people, so results may not apply to everyone. Risks include stroke, incomplete aneurysm closure, or need for retreatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRACRANIAL ANEURYSM

Contacts and locations

Locations

Advocate Lutheran General Hospital
SUSPENDED

Park Ridge, Illinois, 60068, United States
Albany Medical Center
RECRUITING

Albany, New York, 12208, United States
Ascension Saint Vincent Hospital - Indianapolis
RECRUITING

Indianapolis, Indiana, 46260-1902, United States
Baptist Medical Center Jacksonville
RECRUITING

Jacksonville, Florida, 32207, United States
Buffalo General Medical Center
RECRUITING

Buffalo, New York, 14203, United States
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
Cooper University Health
RECRUITING

Camden, New Jersey, 08103, United States
Hospital of the University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Novant Health Brain and Spine Surgery
RECRUITING

Charlotte, North Carolina, 28211, United States
Prisma Health
RECRUITING

Greenville, South Carolina, 29605, United States
Semmes Murphy Clinic
RECRUITING

Memphis, Tennessee, 38120, United States
Stony Brook University Hospital
RECRUITING

Stony Brook, New York, 11794, United States
Swedish Medical Center
RECRUITING

Englewood, Colorado, 80113-2764, United States
Tampa General Hospital
RECRUITING

Tampa, Florida, 33606, United States
The Mount Sinai Hospital
RECRUITING

New York, New York, 10029, United States
Thomas Jefferson University Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
UPMC Presbyterian
RECRUITING

Pittsburgh, Pennsylvania, 15213-2536, United States
University of Chicago
RECRUITING

Chicago, Illinois, 60673, United States
University of Iowa Hospitals and Clinics
RECRUITING

Iowa City, Iowa, 52242, United States
University of Utah Hospital
RECRUITING

Salt Lake City, Utah, 84132, United States
West Virginia University
RECRUITING

Morgantown, West Virginia, 26506-9260, United States
Yale New Haven Hospital
RECRUITING

New Haven, Connecticut, 06519, United States

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