New Blood-Cleaning machine could help liver failure patients avoid transplant
NCT ID NCT07329036
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a combined blood-filtering system (DPMAS and plasma exchange) in 25 adults with acute-on-chronic liver failure who are either waiting for a liver transplant or not eligible for one. The goal is to see if this artificial liver support can keep patients alive without a transplant for at least 21 days. The treatment aims to remove toxins from the blood and support vital organ function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Double Plasma Molecular Adsorption System (DPMAS) combined with Therapeutic Plasma Exchange (TPE)
- What this could lead to
- If it works, this could provide a temporary liver support option for patients with acute liver failure, potentially reducing the need for urgent liver transplants.
- What could go wrong
- This is a small early study with only 25 participants, so results may not apply broadly. The treatment is supportive, not a cure, and risks include bleeding or infection from the blood-filtering procedure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institute for Clinical and Experimental Medicine (IKEM)
RECRUITINGPrague, 14200, Czechia
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Other studies related to the condition(s) this trial covers.
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