New drug could improve breast cancer treatment before surgery
NCT ID NCT05900206
First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 24 times
Summary
This study compares a new drug, trastuzumab deruxtecan (T-DXd), with standard treatment given before surgery for HER2-positive breast cancer that has not spread. About 370 adults will receive either T-DXd or standard therapy for three cycles, then further treatment is chosen based on the tumor's molecular type. The goal is to see if T-DXd leads to more complete tumor disappearance at surgery and to find markers that predict which treatment works best.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Karolinska University Hospital
RECRUITINGStockholm, 17164, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Norrlands University Hospital
NOT_YET_RECRUITINGUmeå, 90185, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sankt Gorans Hospital
NOT_YET_RECRUITINGStockholm, 11219, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Skåne University Hospital
NOT_YET_RECRUITINGMalmö, 21428, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stockholm Southern Hospital
NOT_YET_RECRUITINGStockholm, 11861, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Uppsala University Hospital
NOT_YET_RECRUITINGUppsala, 75185, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Örebro University Hospital
NOT_YET_RECRUITINGÖrebro, 70185, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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