New drug trial aims to tame uncontrollable hunger in rare genetic disorder

NCT ID NCT07197034

Summary

This study is testing whether ARD-101 can safely help control the extreme, life-threatening hunger experienced by people with Prader-Willi syndrome over a full year. It follows 90 patients who previously participated in a related 12-week trial, asking them to take the medication daily and track their symptoms. The main goal is to see if the drug continues to reduce dangerous food-seeking behaviors and remains safe with long-term use.

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Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, 16499, South Korea

  • Alberta Children's Hospital Research Institute

    Calgary, Alberta, T3B 6A8, Canada

  • Ann and Robert H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611-2991, United States

  • Centre Hospitalier Universitaire Sainte-Justine

    Montreal, Quebec, H3T 1C5, Canada

  • Children's Hospital Colorado

    Denver, Colorado, 80045-7106, United States

  • Children's Hospital at London Health Sciences Centre

    London, Ontario, N6A 5W9, Canada

  • Children's Hospital of Orange Country

    Orange, California, 92868, United States

  • Children's of Alabama

    Birmingham, Alabama, 35233-1711, United States

  • Cook Children's Medical Center

    Fort Worth, Texas, 76104, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30322-1047, United States

  • Fulborn Hospital

    Cambridge, CB21 5EF, United Kingdom

  • Inha University Hospital

    Incheon, 22332, South Korea

  • Leicester Royal Infirmary

    Leicester, LE1 5WW, United Kingdom

  • Maimonides Medical Center

    Brooklyn, New York, 11219-2918, United States

  • NYU Langone Children's Ambulatory Care Center

    Mineola, New York, 11501-4077, United States

  • Nemours Children's Clinic Wilmington

    Wilmington, Delaware, 19803-3607, United States

  • Queensland Children's Hospital

    South Brisbane, Queensland, 4101, Australia

  • Rady Children's Hospital

    San Diego, California, 92123, United States

  • Royal Hospital for Children (Glasgow) - PPDS - PIN

    Glasgow, G51 4TF, United Kingdom

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050, Australia

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • Stanford Children's Health Specialty Services

    Palo Alto, California, 94304, United States

  • Stollery Children's Hospital

    Edmonton, Alberta, Canada

  • The Children's Hospital at Westmead

    Westmead, New South Wales, 2145, Australia

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21287-0005, United States

  • The Royal London Hospital

    London, E1 1BB, United Kingdom

  • UF Shands Children's Hospital

    Gainesville, Florida, 32610-3008, United States

  • University of Minnesota Masonic Children's Hospital

    Minneapolis, Minnesota, 55102, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232-0005, United States

Conditions

Explore the condition pages connected to this study.